Quick Overview for OPAL1 antibody (AA 152-342) (PE) (ABIN2749162)
Target
OPAL1 (WBP1L)
(WW Domain Binding Protein 1 Like (WBP1L))
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Conjugate
This OPAL1 antibody is conjugated to PE
Application
Intracellular Flow Cytometry (ICFC)
Clone
OPAL1-01
Binding Specificity
AA 152-342
Purpose
Anti-OPAL1 PE
Specificity
The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.
Cross-Reactivity (Details)
Human
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogen
Recombinant fragment of human OPAL1 (amino acids 152-342)
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Target
OPAL1 (WBP1L)
(WW Domain Binding Protein 1 Like (WBP1L))
Alternative Name
OPAL1
Background
WW domain binding protein 1 like,OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.,WBP1L