OPAL1 antibody (AA 152-342)

Catalog No. ABIN2749167

The Mouse Monoclonal anti-OPAL1 antibody is suitable to detect OPAL1 in samples from Human. It has been validated for WB and FACS.

Quick Overview for OPAL1 antibody (AA 152-342) (ABIN2749167)

Target: OPAL1 (WBP1L) (WW Domain Binding Protein 1 Like (WBP1L))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OPAL1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: OPAL1-01

Product Details anti-OPAL1 Antibody

Binding Specificity: AA 152-342

Purpose: Anti-OPAL1 Purified

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Recombinant fragment of human OPAL1 (amino acids 152-342)

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL, intracellular staining.
Western blotting: Recommended dilution: 1-2 μg/mL, non-reducing conditions.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for OPAL1

Target: OPAL1 (WBP1L) (WW Domain Binding Protein 1 Like (WBP1L))

Alternative Name: OPAL1

Background: WW domain binding protein 1 like,OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.,WBP1L

Gene ID: 54838

UniProt: Q9NX94