PD-1 antibody

Catalog No. ABIN2764099

This Rabbit Polyclonal antibody specifically detects PD-1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for PD-1 antibody (ABIN2764099)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PD-1 Antibody

Cross-Reactivity: Human

Characteristics: CD279, PD1,Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.

Purification: Antigen Immunoaffiinity Purification

Immunogen: Synthetic peptide derived from the human PD1 protein.

Isotype: Ig Fraction

Application Details

Application Notes: Antibody can be used for immunohistochemistry (2-4 μg/mL) and Western blotting (1-2 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: Programmed cell death protein 1

UniProt: Q15116

Pathways: Cancer Immune Checkpoints