Growth Hormone 2 antibody (Middle Region)
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- Target See all Growth Hormone 2 (GH2) Antibodies
- Growth Hormone 2 (GH2)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Goat, Horse, Pig, Rabbit, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Growth Hormone 2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NQSYSKFDTK SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC
- Predicted Reactivity
- Cow: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GH2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GH2
- Top Product
- Discover our top product GH2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 202 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Growth Hormone 2 (GH2)
- Alternative Name
- GH2 (GH2 Products)
- Synonyms
- GH-V antibody, GHL antibody, GHV antibody, hGH-V antibody, growth hormone 2 antibody, GH2 antibody
- Background
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GH2 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Mutations in its gene lead to placental growth hormone/lactogen deficiency.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency.
Alias Symbols: GH-V, GHL, GHV, hGH-V
Protein Interaction Partner: GHR,
Protein Size: 202 - Molecular Weight
- 22 kDa
- Gene ID
- 2689
- NCBI Accession
- NM_022556, NP_072050
- UniProt
- O14643
- Pathways
- NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus
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