FBXO24 antibody (N-Term)

Catalog No. ABIN2773818

This Rabbit Polyclonal antibody specifically detects FBXO24 in WB. It exhibits reactivity toward Human.

Quick Overview for FBXO24 antibody (N-Term) (ABIN2773818)

Target: FBXO24 (F-Box Protein 24 (FBXO24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO24 Antibody

Binding Specificity: N-Term

Sequence: MGEKAVPLLR RRRVKRSCPS CGSELGVEEK RGKGNPISIQ LFPPELVEHI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO24

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 580 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO24

Target: FBXO24 (F-Box Protein 24 (FBXO24))

Alternative Name: FBXO24

Background: FBXO24 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class. Alternative splicing of this gene generates two transcript variants. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates two transcript variants.
Alias Symbols: DKFZp434I1122, FBX24
Protein Interaction Partner: HSP90AA1,
Protein Size: 580

Molecular Weight: 65 kDa

Gene ID: 26261

NCBI Accession: NM_033506, NP_277041

UniProt: O75426