SP1 antibody (Middle Region)

Catalog No. ABIN310487

The Rabbit Polyclonal anti-SP1 antibody is suitable to detect SP1 in samples from Human, Mouse, Rat, Cow, Dog, Goat, Pig, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for SP1 antibody (Middle Region) (ABIN310487)

Target: SP1 (Sp1 Transcription Factor (SP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SP1 Antibody

Binding Specificity: Middle Region

Sequence: TLTPIASAAS IPAGTVTVNA AQLSSMPGLQ TINLSALGTS GIQVHPIQGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 785 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SP1

Target: SP1 (Sp1 Transcription Factor (SP1))

Alternative Name: SP1

Background: SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.
Alias Symbols: -
Protein Interaction Partner: JUN, UBC, HIC1, HDAC1, SP3, TP53, CTNNB1, ARHGAP21, SENP6, C3orf17, USP39, FOXM1, ESR1, DDX5, KIF1A, PPIG, TPI1, TFAP2A, NAP1L1, HDAC2, NUP62, MYC, HIF1A, POU2F1, SMAD3, DDX3X, TBP, SP1, RBL1, Taf4, tat, ESR2, VHL, YY1, CASP7, CASP6, CASP3, HTT, BRCA1, MA
Protein Size: 785

Molecular Weight: 81 kDa

Gene ID: 6667

NCBI Accession: NM_138473, NP_612482

UniProt: P08047

Pathways: Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction