TSPAN4 antibody (Middle Region)

Catalog No. ABIN2773851

The Rabbit Polyclonal anti-TSPAN4 antibody has been validated for WB. It is suitable to detect TSPAN4 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig and Horse.

Quick Overview for TSPAN4 antibody (Middle Region) (ABIN2773851)

Target: TSPAN4 (Tetraspanin 4 (TSPAN4))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPAN4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSPAN4 Antibody

Binding Specificity: Middle Region

Sequence: YTDKIDRYAQ QDLKKGLHLY GTQGNVGLTN AWSIIQTDFR CCGVSNYTDW

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TSPAN4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TSPAN4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSPAN4

Target: TSPAN4 (Tetraspanin 4 (TSPAN4))

Alternative Name: TSPAN4

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: NAG-2, NAG2, TETRASPAN, TM4SF7, TSPAN-4
Protein Interaction Partner: NOTCH2NL, UBC, CD81, ITGA3, CLDN11, ITGA6, CD9, ITGB1, CD46,
Protein Size: 238

Molecular Weight: 26 kDa

Gene ID: 7106

NCBI Accession: NM_001025234, NP_001020405

UniProt: O14817