MAP4K1 antibody (N-Term)

Catalog No. ABIN2773872

The Rabbit Polyclonal anti-MAP4K1 antibody has been validated for WB. It is suitable to detect MAP4K1 in samples from Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for MAP4K1 antibody (N-Term) (ABIN2773872)

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP4K1 Antibody

Binding Specificity: N-Term

Sequence: VHPLRVLFLM TKSGYQPPRL KEKGKWSAAF HNFIKVTLTK SPKKRPSATK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MAP4K1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 821 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP4K1

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Alternative Name: MAP4K1

Background: MAP4K1 belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily. MAP4K1 may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K1 may play a role in hematopoietic lineage decisions and growth regulation.
Alias Symbols: HPK1
Protein Interaction Partner: FBXW7, FBXW8, MAP4K1, UBC, SKP1, PPP4C, RBX1, CUL7, TMEM101, HSP90AA1, NCK1, LRRK1, SPRY1, GRAP2, COPS5, DBNL, DAPP1, BLNK, MAP3K7, LAT, CRKL, LCP2, HCLS1, CASP3, SHC1, SYK, MAP3K11, ABL1, LYN, CRK, EGFR, GRB2,
Protein Size: 821

Molecular Weight: 90 kDa

Gene ID: 11184

NCBI Accession: NM_001042600, NP_001036065

UniProt: A8MWC4

Pathways: TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor