DPP3 antibody (N-Term)

Catalog No. ABIN2773875

This Rabbit Polyclonal antibody specifically detects DPP3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog and Rabbit.

Quick Overview for DPP3 antibody (N-Term) (ABIN2773875)

Target: DPP3 (Dipeptidyl-Peptidase 3 (DPP3))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DPP3 Antibody

Binding Specificity: N-Term

Sequence: SRAAWYGGLA VLLQTSPEAP YIYALLSRLF RAQDPDQLRQ HALAEGLTEE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DPP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DPP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 737 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DPP3

Target: DPP3 (Dipeptidyl-Peptidase 3 (DPP3))

Alternative Name: DPP3

Background: DPP3 is a protein that is a member of the S9B family in clan SC of the serine proteases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers.This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.
Alias Symbols: DPPIII, FLJ11387, FLJ22331
Protein Interaction Partner: KEAP1, UBC, NHLRC2, TNFAIP8, NDRG1, TRIP6, SMS, SGTA, PEPD, DLD, ASS1, LIG4, APP, DSTN, TERF2IP, TINF2, POT1, TERF1, SUMO2, HSPA8, ATP5C1,
Protein Size: 737

Molecular Weight: 82 kDa

Gene ID: 10072

NCBI Accession: NM_005700, NP_005691

UniProt: Q9NY33