SC4MOL antibody (N-Term)

Catalog No. ABIN310847

The Rabbit Polyclonal anti-SC4MOL antibody has been validated for WB. It is suitable to detect SC4MOL in samples from Human, Mouse, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig, Rat and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for SC4MOL antibody (N-Term) (ABIN310847)

Target: SC4MOL (MSMO1) (Methylsterol Monooxygenase 1 (MSMO1))

Reactivity: Human, Mouse, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SC4MOL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SC4MOL Antibody

Binding Specificity: N-Term

Sequence: MATNESVSIF SSASLAVEYV DSLLPENPLQ EPFKNAWNYM LNNYTKFQIA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SC4MOL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SC4MOL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 293 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SC4MOL antibody (ABIN310847)

Li, Yang, Wang, Li, Wu, Zhang, Qi, Zhang, Li: "Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma." in: International journal of biological sciences, Vol. 18, Issue 9, pp. 3576-3591, (2022) (PubMed).

Target Details for SC4MOL

Target: SC4MOL (MSMO1) (Methylsterol Monooxygenase 1 (MSMO1))

Alternative Name: SC4MOL

Background: Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases.Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DESP4, ERG25, MGC104344, SC4MOL
Protein Interaction Partner: UBC, VKORC1, DDRGK1, IMMT, EIF3F, EIF3A, PDHA2, ATXN1, ELAVL1,
Protein Size: 293

Molecular Weight: 35 kDa

Gene ID: 6307

NCBI Accession: NM_006745, NP_006736

UniProt: Q15800