CDR2 antibody (N-Term)

Catalog No. ABIN2773981

The Rabbit Polyclonal anti-CDR2 antibody has been validated for IHC and WB. It is suitable to detect CDR2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CDR2 antibody (N-Term) (ABIN2773981)

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CDR2 Antibody

Binding Specificity: N-Term

Sequence: MLAENLVEEF EMKEDEPWYD HQDLQQDLQL AAELGKTLLD RNTELEDSVQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against CDR2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 454 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDR2

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Alternative Name: CDR2

Background: Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.
Alias Symbols: CDR62, Yo
Protein Interaction Partner: SMARCE1, CEP57L1, KANSL1, CCDC153, C4orf46, TXLNA, ALS2CR11, C1orf216, HAUS1, ANKRD36BP1, TCHP, FAM161A, ENKD1, FAM110A, LENG1, SCNM1, SH2D4A, LIN37, RCOR3, TBC1D22B, WDYHV1, CCHCR1, AMOTL2, FZR1, RSPH14, CHIC2, MRPL28, TMCC2, HDAC4, EIF4E2, TTR, COX5B, T
Protein Size: 454

Molecular Weight: 52 kDa

Gene ID: 1039

NCBI Accession: NM_001802, NP_001793

UniProt: Q01850