Septin 9 antibody (Middle Region)

Catalog No. ABIN2773992

This Rabbit Polyclonal antibody specifically detects Septin 9 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Zebrafish (Danio rerio), Cow, Dog, Horse and Rabbit.

Quick Overview for Septin 9 antibody (Middle Region) (ABIN2773992)

Target: Septin 9 (SEPT9)

Reactivity: Human, Mouse, Rat, Guinea Pig, Zebrafish (Danio rerio), Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Septin 9 Antibody

Binding Specificity: Middle Region

Sequence: VNEKFREMIP FAVVGSDHEY QVNGKRILGR KTKWGTIEVE NTTHCEFAYL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SEPT9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEPT9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 422 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Septin 9

Target: Septin 9 (SEPT9)

Alternative Name: SEPT9

Background: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: AF17q25, KIAA0991, MSF, MSF1, NAPB, PNUTL4, SINT1, SeptD1
Protein Interaction Partner: SEPT6, HAUS1, SUMO2, UBC, EED, HNRNPD, FN1, CFTR, VAMP2, SVIL, SCP2, NDUFV2, NCL, MSH2, HSPD1, FLNB, COPA, SEPT7, APP, UQCRFS1P1, UQCRFS1, TPM3, SUCLG2, VMA21, SEPT11, TMED9, HN1, TOR1AIP1, FERMT2, TIMM44, HRSP12, SCO2, SEC22B, VAPB, SUCLG1, UBXN6, UBD, S
Protein Size: 422

Molecular Weight: 46 kDa

Gene ID: 10801

NCBI Accession: NM_001113492, NP_001106964

UniProt: Q9UHD8