RHEBL1 antibody (Middle Region)

Catalog No. ABIN2774023

This Rabbit Polyclonal antibody specifically detects RHEBL1 in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat and Pig.

Quick Overview for RHEBL1 antibody (Middle Region) (ABIN2774023)

Target: RHEBL1 (Ras Homolog Enriched in Brain Like 1 (RHEBL1))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHEBL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RHEBL1 Antibody

Binding Specificity: Middle Region

Sequence: TRVPVVLVGN KADLSPEREV QAVEGKKLAE SWGATFMESS ARENQLTQGI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against RHEBL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RHEBL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 183 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHEBL1

Target: RHEBL1 (Ras Homolog Enriched in Brain Like 1 (RHEBL1))

Alternative Name: RHEBL1

Background: RHEBL1 binds GTP and exhibits intrinsic GTPase activity. It may activate NF-kappa-B-mediated gene transcription. RHEBL1 promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Alias Symbols: FLJ25797, MGC34869, RHEBL1c
Protein Interaction Partner: APPL1, PRKAB2, MTOR, FHL3, TXNL4A, Blzf1, Traf2, BMPR1B, EIF4EBP1, SMAD1, SMAD2, SMAD4, TGFBR1, AKT1, ACVR1,
Protein Size: 183

Molecular Weight: 21 kDa

Gene ID: 121268

NCBI Accession: NM_144593, NP_653194

UniProt: Q8TAI7