HIPK4 antibody (Middle Region)

Catalog No. ABIN2774025

The Rabbit Polyclonal anti-HIPK4 antibody (ABIN2774025) specifically detects HIPK4 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for HIPK4 antibody (Middle Region) (ABIN2774025)

Target: HIPK4 (Homeodomain Interacting Protein Kinase 4 (HIPK4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIPK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIPK4 Antibody

Binding Specificity: Middle Region

Sequence: AEEKEAAGMG SVAGSSPFFR EEKAPGMQRA IDQLDDLSLQ EAGHGLWGET

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HIPK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIPK4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 616 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIPK4

Target: HIPK4 (Homeodomain Interacting Protein Kinase 4 (HIPK4))

Alternative Name: HIPK4

Background: HIPK4 is a protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. It may act as a corepressor of transcription factors.
Alias Symbols: FLJ32818
Protein Interaction Partner: APPBP2, PFKP, HIPK4, SFXN2, TRABD, LPCAT1, YTHDF2, ZNF281, NUP188, WDR6, AFG3L2, YME1L1, AKAP8, SUGP2, TECR, UBL4A, ZNF146, RCN1, RBBP4, RAF1, ABCD3, MCM7, LBR, ACSL3, EEF2, CTSB, CDKN2A, ATP1A1, ARAF, HSP90AA1,
Protein Size: 616

Molecular Weight: 69 kDa

Gene ID: 147746

NCBI Accession: NM_144685, NP_653286

UniProt: Q8NE63