HIPK4 antibody (Middle Region)

Catalog No. ABIN2774025

This anti-HIPK4 antibody is a Rabbit Polyclonal antibody detecting HIPK4 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for HIPK4 antibody (Middle Region) (ABIN2774025)

Target: HIPK4 (Homeodomain Interacting Protein Kinase 4 (HIPK4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIPK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIPK4 Antibody

Binding Specificity: Middle Region

Sequence: AEEKEAAGMG SVAGSSPFFR EEKAPGMQRA IDQLDDLSLQ EAGHGLWGET

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HIPK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIPK4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 616 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIPK4

Target: HIPK4 (Homeodomain Interacting Protein Kinase 4 (HIPK4))

Alternative Name: HIPK4

Background: HIPK4 is a protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. It may act as a corepressor of transcription factors.
Alias Symbols: FLJ32818
Protein Interaction Partner: APPBP2, PFKP, HIPK4, SFXN2, TRABD, LPCAT1, YTHDF2, ZNF281, NUP188, WDR6, AFG3L2, YME1L1, AKAP8, SUGP2, TECR, UBL4A, ZNF146, RCN1, RBBP4, RAF1, ABCD3, MCM7, LBR, ACSL3, EEF2, CTSB, CDKN2A, ATP1A1, ARAF, HSP90AA1,
Protein Size: 616

Molecular Weight: 69 kDa

Gene ID: 147746

NCBI Accession: NM_144685, NP_653286

UniProt: Q8NE63