PPAPDC2 antibody (N-Term)

Catalog No. ABIN2774128

The Rabbit Polyclonal anti-PPAPDC2 antibody is suitable to detect PPAPDC2 in samples from Human, Mouse, Rat, Dog, Cow, Pig and Rabbit. It has been validated for WB.

Quick Overview for PPAPDC2 antibody (N-Term) (ABIN2774128)

Target: PPAPDC2 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAPDC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPAPDC2 Antibody

Binding Specificity: N-Term

Sequence: MPSPRRSMEG RPLGVSASSS SSSPGSPAHG GGGGGSRFEF QSLLSSRATA

Predicted Reactivity: Cow: 100%, Dog: 86%, Human: 100%, Mouse: 79%, Pig: 81%, Rabbit: 93%, Rat: 87%

Characteristics: This is a rabbit polyclonal antibody against PPAPDC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPAPDC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPAPDC2

Target: PPAPDC2 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))

Alternative Name: PPAPDC2

Background: PPAPDC2 is the phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.
Alias Symbols: FLJ46512, FLJ90191, MGC15483, PSDP, bA6J24.6, PDP1
Protein Interaction Partner: UBC,
Protein Size: 295

Molecular Weight: 32 kDa

Gene ID: 403313

NCBI Accession: NM_203453, NP_982278

UniProt: Q8IY26