SFRS7 antibody (N-Term)

Catalog No. ABIN2774137

The Rabbit Polyclonal anti-SFRS7 antibody has been validated for WB. It is suitable to detect SFRS7 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for SFRS7 antibody (N-Term) (ABIN2774137)

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SFRS7 Antibody

Binding Specificity: N-Term

Sequence: MSRYGRYGGE TKVYVGNLGT GAGKGELERA FSYYGPLRTV WIARNPPGFA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRS7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SFRS7 antibody (ABIN2774137)

Swartz, Bor, Misawa, Rekosh, Hammarskjold: "The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element." in: The Journal of biological chemistry, Vol. 282, Issue 27, pp. 19844-53, (2007) (PubMed).

Target Details for SFRS7

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Alternative Name: SFRS7

Background: SFRS7 is required for pre-mRNA splicing. SFRS7 can also modulate alternative splicing in vitro.
Alias Symbols: 9G8, AAG3, HSSG1, RBM37, ZCCHC20, ZCRB2, SFRS7
Protein Interaction Partner: LUC7L2, SDCBP, RELA, CEP250, UBC, STAU1, ZBTB1, EZH2, SUZ12, EED, NEDD4, TARDBP, CLK3, SRPK2, SRPK1, YWHAE, PAN2, CDK6, MAGOH, EIF4A3, HNF1A, ESR1, BARD1, PAXIP1, ZRANB2, TM9SF2, SRSF11, DDX21, PRPF3, SART1, BUD31, U2AF1, TFPI, SURF4, SON, SNRPA1, TRA2B,
Protein Size: 238

Molecular Weight: 27 kDa

Gene ID: 6432

NCBI Accession: NM_001031684, NP_001026854

UniProt: Q16629