Neurotrophin 4 antibody (N-Term)

Catalog No. ABIN2774156

The Rabbit Polyclonal anti-Neurotrophin 4 antibody has been validated for WB. It is suitable to detect Neurotrophin 4 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow and Rabbit. There is 1 publication available.

Quick Overview for Neurotrophin 4 antibody (N-Term) (ABIN2774156)

Target: Neurotrophin 4 (NTF4)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurotrophin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neurotrophin 4 Antibody

Binding Specificity: N-Term

Sequence: LAPEWDLLSP RVVLSRGAPA GPPLLFLLEA GAFRESAGAP ANRSRRGVSE

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against NTF5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NTF5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 210 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Neurotrophin 4 antibody (ABIN2774156)

Mercader, Saus, Agüera, Bayés, Boni, Carreras, Cellini, de Cid, Dierssen, Escaramís, Fernández-Aranda, Forcano, Gallego, González, Gorwood, Hebebrand, Hinney, Nacmias, Puig, Ribasés, Ricca, Romo, Sorbi, Versini, Gratacòs, Estivill: "Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders." in: Human molecular genetics, Vol. 17, Issue 9, pp. 1234-44, (2008) (PubMed).

Target Details for Neurotrophin 4

Target: Neurotrophin 4 (NTF4)

Alternative Name: NTF5

Background: This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neu
Alias Symbols: NT-4/5, NT4, NT5, NTF4, NT-4, NT-5, NTF5, GLC10, GLC1O
Protein Interaction Partner: ADAMTSL4, CLIC1, NTRK2, NTF4, NGFR, BDNF,
Protein Size: 210

Molecular Weight: 22 kDa

Gene ID: 4909

NCBI Accession: NM_006179, NP_006170

UniProt: P34130

Pathways: RTK Signaling