Syntaxin 4 antibody (C-Term)

Catalog No. ABIN2774260

This Rabbit Polyclonal antibody specifically detects Syntaxin 4 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Pig, Rabbit, Dog, Horse and Guinea Pig.

Quick Overview for Syntaxin 4 antibody (C-Term) (ABIN2774260)

Target: Syntaxin 4 (STX4)

Reactivity: Human, Rat, Mouse, Cow, Pig, Rabbit, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Syntaxin 4 Antibody

Binding Specificity: C-Term

Sequence: VEMQGEMINR IEKNILSSAD YVERGQEHVK TALENQKKAR KKKVLIAICV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 91%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against STX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human STX4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Syntaxin 4

Target: Syntaxin 4 (STX4)

Alternative Name: STX4

Background: STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes . STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.
Alias Symbols: STX4A, p35-2
Protein Interaction Partner: BET1, STX6, GOSR2, STX8, VAMP3, STX16, VAMP4, STX7, UBC, VAMP2, VAMP1, STX5, STX4, STX3, PSMA3, SNAP47, CYBRD1, NAPB, GIMAP5, SEC22A, STX12, VAMP5, VTI1B, UBL4A, FN1, NDUFB9, ABCC1, SLC25A10, ANXA3, SNAP23, ITSN2, SNAP25, STXBP4, SYT7, TXLNB, STXBP3, TXLN
Protein Size: 297

Molecular Weight: 34 kDa

Gene ID: 6810

NCBI Accession: NM_004604, NP_004595

UniProt: Q12846

Pathways: Synaptic Vesicle Exocytosis