MYOC antibody (N-Term)

Catalog No. ABIN2774268

This Rabbit Polyclonal antibody specifically detects MYOC in WB. It exhibits reactivity toward Human, Rat and Guinea Pig.

Quick Overview for MYOC antibody (N-Term) (ABIN2774268)

Target: MYOC (Myocilin (MYOC))

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYOC Antibody

Binding Specificity: N-Term

Sequence: QLTLDQAARP QETQEGLQRE LGTLRRERDQ LETQTRELET AYSNLLRDKS

Predicted Reactivity: Guinea Pig: 86%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MYOC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYOC

Target: MYOC (Myocilin (MYOC))

Alternative Name: MYOC

Background: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Alias Symbols: GPOA, JOAG, TIGR, GLC1A, JOAG1, myocilin
Protein Size: 344

Molecular Weight: 37 kDa

Gene ID: 4653

NCBI Accession: NM_000261, NP_000252

UniProt: Q99972