Adenosine A2a Receptor antibody (N-Term)

Catalog No. ABIN2774274

This Rabbit Polyclonal antibody specifically detects Adenosine A2a Receptor in WB. It exhibits reactivity toward Human, Rat, Dog and Rabbit.

Quick Overview for Adenosine A2a Receptor antibody (N-Term) (ABIN2774274)

Target: Adenosine A2a Receptor (ADORA2A)

Reactivity: Human, Rat, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A2a Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adenosine A2a Receptor Antibody

Binding Specificity: N-Term

Sequence: SFAIGLTPML GWNNCGQPKE GKNHSQGCGE GQVACLFEDV VPMNYMVYFN

Predicted Reactivity: Dog: 86%, Human: 100%, Rabbit: 85%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against ADORA2A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADORA2A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenosine A2a Receptor

Target: Adenosine A2a Receptor (ADORA2A)

Alternative Name: ADORA2A

Background: ADORA2A is one of several receptor subtypes for adenosine. The activity of the protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. ADORA2A is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
Alias Symbols: ADORA2, RDC8, hA2aR
Protein Interaction Partner: NAMPT, Actn1, Actn4, Actn3, Actn2, ADORA2A, CYTH2, DRD2, ADA,
Protein Size: 412

Molecular Weight: 45 kDa

Gene ID: 135

NCBI Accession: NM_000675, NP_000666

UniProt: P29274

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints