CD42a antibody (Middle Region)

Catalog No. ABIN2774317

This Rabbit Polyclonal antibody specifically detects CD42a in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig, Rabbit, Cow and Saccharomyces cerevisiae.

Quick Overview for CD42a antibody (Middle Region) (ABIN2774317)

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD42a antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD42a Antibody

Binding Specificity: Middle Region

Sequence: NSLQSVPPGA FDHLPQLQTL DVTQNPWHCD CSLTYLRLWL EDRTPEALLQ

Predicted Reactivity: Cow: 92%, Dog: 93%, Human: 100%, Mouse: 86%, Pig: 83%, Rabbit: 86%, Rat: 86%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against GP9. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 177 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD42a

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Alternative Name: GP9

Background: This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Alias Symbols: CD42a, GPIX
Protein Interaction Partner: SPRY2, HOXA1, APPBP2, GP1BA, GP1BB,
Protein Size: 177

Molecular Weight: 19 kDa

Gene ID: 2815

NCBI Accession: NM_000174, NP_000165

UniProt: P14770