TUBB3 antibody (C-Term)
Quick Overview for TUBB3 antibody (C-Term) (ABIN2774381)
Target
See all TUBB3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- EGMDEMEFTE AESNMNDLVS EYQQYQDATA EEEGEMYEDD EEESEAQGPK
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 90%
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Characteristics
- This is a rabbit polyclonal antibody against TUBB3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 450 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TUBB3 (Tubulin, beta 3 (TUBB3))
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Alternative Name
- TUBB3
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Background
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This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
Alias Symbols: CFEOM3A, MC1R, TUBB4, beta-4, CDCBM
Protein Interaction Partner: UBC, HAUS2, CEP250, MAPT, EMD, EML1, ASB18, ASB8, ASB17, ASB4, rev, PAPSS1, VCL, RARS, MSN, STK26, CAPZB, CAPZA1, ACAT2, FBXO6, EGFR, CD81, HDAC6, SOX2, NPM1, IQCB1, TPTE, FAM86B2, METTL23, CAMKMT, VCPKMT, METTL22, METTL21B, PEX14, GZMK, TUBA1C, MDN1, TUB
Protein Size: 450 -
Molecular Weight
- 50 kDa
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Gene ID
- 10381
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NCBI Accession
- NM_006086, NP_006077
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UniProt
- Q13509
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Pathways
- Microtubule Dynamics, M Phase
Target
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