FGF17 antibody (Middle Region)

Catalog No. ABIN2774391

This anti-FGF17 antibody is a Rabbit Polyclonal antibody detecting FGF17 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for FGF17 antibody (Middle Region) (ABIN2774391)

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGF17 Antibody

Binding Specificity: Middle Region

Sequence: KLIVETDTFG SRVRIKGAES EKYICMNKRG KLIGKPSGKS KDCVFTEIVL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FGF17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FGF17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 216 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FGF17

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Alternative Name: FGF17

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development. This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.
Alias Symbols: FGF-13
Protein Interaction Partner: FGFR2, FGFR1, FGFR4, FGFR3,
Protein Size: 216

Molecular Weight: 23 kDa

Gene ID: 8822

NCBI Accession: NM_003867, NP_003858

UniProt: O60258

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway