DSN1 antibody (C-Term)

Catalog No. ABIN2774435

The Rabbit Polyclonal anti-DSN1 antibody is suitable to detect DSN1 in samples from Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for DSN1 antibody (C-Term) (ABIN2774435)

Target: DSN1 (Kinetochore-associated protein DSN1 homolog (DSN1))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DSN1 Antibody

Binding Specificity: C-Term

Sequence: MTYLGSSQNE VLNTKPDYQK ILQNQSKVFD CMELVMDELQ GSVKQLQAFM

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DSN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DSN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 249 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DSN1

Target: DSN1 (Kinetochore-associated protein DSN1 homolog (DSN1))

Alternative Name: DSN1

Background: This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.
Alias Symbols: C20orf172, FLJ13346, KNL3, MGC32987, MIS13, dJ469A13.2, hKNL-3
Protein Interaction Partner: ZWINT, SUGT1, CBX5, APP, MIS12, NSL1, PMF1, HSP90AA1, SKA2, UBC, SUMO2, PIK3R3, AIMP2, Casc5, Ndc80, Dsn1, Bub1b, Bub1, CBX3,
Protein Size: 249

Molecular Weight: 28 kDa

Gene ID: 79980

NCBI Accession: NM_001145317, NP_001138789

UniProt: Q5JW55