TTDN1 antibody (Middle Region)

Catalog No. ABIN2774466

The Rabbit Polyclonal anti-TTDN1 antibody is suitable to detect TTDN1 in samples from Human, Cow, Dog, Guinea Pig, Mouse, Rabbit and Rat. It has been validated for WB.

Quick Overview for TTDN1 antibody (Middle Region) (ABIN2774466)

Target: TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))

Reactivity: Human, Cow, Dog, Guinea Pig, Mouse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTDN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TTDN1 Antibody

Binding Specificity: Middle Region

Sequence: PGGYPGSYSR SPAGSQQQFG YSPGQQQTHP QGSPRTSTPF GSGRVREKRM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MPLKIP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MPLKIP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 179 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTDN1

Target: TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))

Alternative Name: MPLKIP

Background: The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.
Alias Symbols: ABHS, C7orf11, ORF20
Protein Interaction Partner: MRPL53, SARNP, SUGP1, CDV3, RBM27, SBDS, SF3B4, PPIF, SCAMP3, SF1, THY1, SCP2, NDUFA7, SERPINH1,
Protein Size: 179

Molecular Weight: 20 kDa

Gene ID: 136647

NCBI Accession: NM_138701, NP_619646

UniProt: Q8TAP9