MRPL44 antibody (C-Term)

Catalog No. ABIN2774515

This Rabbit Polyclonal antibody specifically detects MRPL44 in WB. It exhibits reactivity toward Human, Rat, Dog, Pig and Rabbit.

Quick Overview for MRPL44 antibody (C-Term) (ABIN2774515)

Target: MRPL44 (Mitochondrial Ribosomal Protein L44 (MRPL44))

Reactivity: Human, Rat, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL44 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL44 Antibody

Binding Specificity: C-Term

Sequence: EGPGETVLVA EEEAARVALR KLYGFTENRR PWNYSKPKET LRAEKSITAS

Predicted Reactivity: Dog: 85%, Human: 100%, Pig: 77%, Rabbit: 85%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against MRPL44. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPL44

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 332 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL44

Target: MRPL44 (Mitochondrial Ribosomal Protein L44 (MRPL44))

Alternative Name: MRPL44

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Alias Symbols: L44MT, MRP-L44
Protein Interaction Partner: ABI2, TARDBP, NPM1, PPAP2C, DGKE, C1QBP, MPV17, ILF3, HNRNPU, ATP6V0A1, TMEM177, MRPL24, MRPL9, MRPL32, MRPL38, MRPL41, MRPL47, TSR1, SYNJ2BP, MRPL50, MRPL39, MRPL51, MRPL37, MRPL13, MRPL42, MRPL19, SPCS2, EIF4H, CUL3, TCF3, UBC, ITFG1, CEP70, SEMA5B, NGE
Protein Size: 332

Molecular Weight: 37 kDa

Gene ID: 65080

NCBI Accession: NM_022915, NP_075066

UniProt: Q9H9J2