FBXO7 antibody (Middle Region)

Catalog No. ABIN2774701

The Rabbit Polyclonal anti-FBXO7 antibody has been validated for WB and IP. It is suitable to detect FBXO7 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse and Pig.

Quick Overview for FBXO7 antibody (Middle Region) (ABIN2774701)

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FBXO7 Antibody

Binding Specificity: Middle Region

Sequence: PGETPSQFPP LRPRFDPVGP LPGPNPILPG RGGPNDRFPF RPSRGRPTDG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against FBXO7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 522 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Alternative Name: FBXO7

Background: FBXO7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
Alias Symbols: DKFZp686B08113, FBX, FBX07, FBX7, PKPS, PARK15
Protein Interaction Partner: PSME3, PSMF1, PSMA3, SKP1, TRAF2, MAGED1, SHFM1, PINK1, PARK2, SEC24C, NEDD8, UBC, COPS5, COPS6, CUL1, BIRC2, RBBP6, XPO1, DLGAP5, ELF4, BIRC3, CDK6, UBE2D2, CDC34,
Protein Size: 522

Molecular Weight: 58 kDa

Gene ID: 25793

NCBI Accession: NM_012179, NP_036311

UniProt: Q9Y3I1