PDZRN3 antibody (N-Term)

Catalog No. ABIN2774727

The Rabbit Polyclonal anti-PDZRN3 antibody has been validated for WB. It is suitable to detect PDZRN3 in samples from Human, Mouse, Rat, Cow, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for PDZRN3 antibody (N-Term) (ABIN2774727)

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZRN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDZRN3 Antibody

Binding Specificity: N-Term

Sequence: ELDRFDGDVD PDLKCALCHK VLEDPLTTPC GHVFCAGCVL PWVVQEGSCP

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PDZRN3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDZRN3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDZRN3

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Alternative Name: PDZRN3

Background: PDZRN3 is a E3 ubiquitin-protein ligase. It plays an important role in regulating the surface level of MUSK on myotubes. It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. It might contribute to terminal myogenic differentiation.
Protein Interaction Partner: Dlg4, LNX2, LNX1, UBE2D2, MUSK, PDZRN3, BMPR2, EFNB2,
Protein Size: 729

Molecular Weight: 80 kDa

Gene ID: 23024

Pathways: Skeletal Muscle Fiber Development