RNF125 antibody (Middle Region)

Catalog No. ABIN2774748

This Rabbit Polyclonal antibody specifically detects RNF125 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse and Pig.

Quick Overview for RNF125 antibody (Middle Region) (ABIN2774748)

Target: RNF125 (Ring Finger Protein 125 (RNF125))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF125 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNF125 Antibody

Binding Specificity: Middle Region

Sequence: ENPSSFSGSL IRHLQVSHTL FYDDFIDFNI IEEALIRRVL DRSLLEYVNH

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RNF125. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF125

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 232 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF125

Target: RNF125 (Ring Finger Protein 125 (RNF125))

Alternative Name: RNF125

Background: This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Alias Symbols: FLJ20456, MGC21737, TRAC1, TRAC-1
Protein Interaction Partner: UBC, USP2, PCGF1, TRIM46, CHFR, PML, UBE2D1, UBE2U, UBE2W, UBE2D4, UBE2L6, UBE2N, UBE2L3, UBE2E2, UBE2D3, UBE2D2, UBE2K,
Protein Size: 232

Molecular Weight: 26 kDa

Gene ID: 54941

NCBI Accession: NM_017831, NP_060301

UniProt: Q96EQ8