HACE1 antibody (Middle Region)

Catalog No. ABIN2774769

This Rabbit Polyclonal antibody specifically detects HACE1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog and Horse.

Quick Overview for HACE1 antibody (Middle Region) (ABIN2774769)

Target: HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HACE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HACE1 Antibody

Binding Specificity: Middle Region

Sequence: DVSDWIKNTE YTSGYEREDP VIQWFWEVVE DITQEERVLL LQFVTGSSRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HACE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HACE1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 909 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HACE1

Target: HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))

Alternative Name: HACE1

Background: HACE1 contains 6 ANK repeats and 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. HACE1 is an E3 ubiquitin-protein ligase that may function in cellular proteins degradation.
Alias Symbols: -
Protein Interaction Partner: UBE2L3, UBC, OPTN, Unc45b, Flna, Actn1, Cald1, Lima1, Actn4, Tpm3, Tmod3, Coro1c, Vim, Vcl, Tubb5, Tubb4a, Tpm2, Tpm1, Tcp1, Plec, Sqstm1, Npm1, Myh9, Marcks, Hspa9, Hsp90ab1, Hspd1, Hspa8, Fhl1, Csrp1, Cnn2, Cct8, Serpinh1, Capzb, Capza2, Capza1, Actg1,
Protein Size: 909

Molecular Weight: 102 kDa

Gene ID: 57531

NCBI Accession: NM_020771, NP_065822

UniProt: Q8IYU2