Arc antibody (Middle Region)

Catalog No. ABIN2774829

This anti-Arc antibody is a Rabbit Polyclonal antibody detecting Arc in WB and IHC. Suitable for Human, Rat, Mouse, Guinea Pig, Cow and Goat.

Quick Overview for Arc antibody (Middle Region) (ABIN2774829)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Human, Rat, Mouse, Guinea Pig, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arc antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Arc Antibody

Binding Specificity: Middle Region

Sequence: ELDLPQKQGE PLDQFLWRKR DLYQTLYVDA DEEEIIQYVV GTLQPKLKRF

Predicted Reactivity: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 396 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: ARC

Background: ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.
Alias Symbols: KIAA0278, Arg3.1
Protein Interaction Partner: UBE3A, UBC, KRT15,
Protein Size: 396

Molecular Weight: 45 kDa

Gene ID: 23237

NCBI Accession: NM_015193, NP_056008

UniProt: Q7LC44