ANXA6 antibody (N-Term)

Catalog No. ABIN2774842

The Rabbit Polyclonal anti-ANXA6 antibody has been validated for WB. It is suitable to detect ANXA6 in samples from Human, Mouse, Rat, Guinea Pig, Cow, Dog, Rabbit, Horse, Pig and Zebrafish (Danio rerio).

Quick Overview for ANXA6 antibody (N-Term) (ABIN2774842)

Target: ANXA6 (Annexin A6 (ANXA6))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Rabbit, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANXA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANXA6 Antibody

Binding Specificity: N-Term

Sequence: ALYTAMKGFG SDKEAILDII TSRSNRQRQE VCQSYKSLYG KDLIADLKYE

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 85%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ANXA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 673 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANXA6

Target: ANXA6 (Annexin A6 (ANXA6))

Alternative Name: ANXA6

Background: Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Alias Symbols: ANX6, CBP68
Protein Interaction Partner: UBC, MDM2, THOP1, PLS3, MTAP, IDH1, HPRT1, GOT1, ADSS, POLE3, NAMPT, UBE2H, ATP4A, METTL18, MLH1, SNCA, CUL5, SIRT7, PRKCA, TJP1, CD4, H2AFX, CDC73, TPD52, S100B, S100A1, RASA1, CR2, A2M, tax,
Protein Size: 673

Molecular Weight: 74 kDa

Gene ID: 309

NCBI Accession: NM_001155, NP_001146

UniProt: P08133