Annexin VII antibody (N-Term)

Catalog No. ABIN2774844

This Rabbit Polyclonal antibody specifically detects Annexin VII in WB. It exhibits reactivity toward Human and Goatand has been mentioned in 1 publication.

Quick Overview for Annexin VII antibody (N-Term) (ABIN2774844)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivity: Human, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VII antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Annexin VII Antibody

Binding Specificity: N-Term

Sequence: GGQMPSQYPG GQPTYPSQPA TVTQVTQGTI RPAANFDAIR DAEILRKAMK

Predicted Reactivity: Goat: 83%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ANXA7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 466 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Annexin VII antibody (ABIN2774844)

Satoh, Nakano, Shibata, Maki: "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner." in: Biochimica et biophysica acta, Vol. 1600, Issue 1-2, pp. 61-7, (2002) (PubMed).

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: ANXA7

Background: Annexin A7 is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
Alias Symbols: SNX, ANX7, SYNEXIN
Protein Interaction Partner: UBC, PAX8, ATP4A, SRC, Prkcb, Prkcg, Prkca, PRKG1, PRKACA, VCP, ANXA4, CUL4B, CUL5, ALG2, ELAVL1, CCDC90B, WDR18, LRIF1, OTUB1, CPSF3L, SEMA5B, INPP5K, ACTL6B, CSAD, SDF4, MED31, TAF5L, TRMT2A, TUBB2B, CPNE2, ZNF431, KLHL23, DOCK7, WDR73, FBN3, RBM48, ADA
Protein Size: 466

Molecular Weight: 51 kDa

Gene ID: 310

NCBI Accession: NM_001156, NP_001147

UniProt: Q5T0M6