CRLF1 antibody (Middle Region)

Catalog No. ABIN2774902

Product Details anti-CRLF1 Antibody

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QLSVRWVSPP ALKDFLFQAK YQIRYRVEDS VDWKVVDDVS NQTSCRLAGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CRLF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRLF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 422 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRLF1

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Alternative Name: CRLF1 (CRLF1 Products)

Background: CRLF1 belongs to the type I cytokine receptor family. It is cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. The protein may be involved in nervous system development.Defects in CRLF1 are the cause of cold-induced sweating syndrome 1 and Crisponi syndrome.
Alias Symbols: CISS, CISS1, CLF, CLF-1, NR6, zcytor5
Protein Interaction Partner: CLCF1, CNTFR,
Protein Size: 422

Molecular Weight: 46 kDa

Gene ID: 9244

NCBI Accession: NM_004750, NP_004741

UniProt: O75462