Annexin V antibody (N-Term)

Catalog No. ABIN2774910

This anti-Annexin V antibody is a Rabbit Polyclonal antibody detecting Annexin V in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Sheep, Horse and Guinea Pig.

Quick Overview for Annexin V antibody (N-Term) (ABIN2774910)

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Sheep, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin V antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Annexin V Antibody

Binding Specificity: N-Term

Sequence: AYELKHALKG AGTNEKVLTE IIASRTPEEL RAIKQVYEEE YGSSLEDDVV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ANXA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 320 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Annexin V

Target: Annexin V (ANXA5) (Annexin A5 (ANXA5))

Alternative Name: ANXA5

Background: ANXA5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
Alias Symbols: PP4, ANX5, ENX2, RPRGL3
Protein Interaction Partner: HUWE1, UBC, FUS, TUBGCP3, ASB9, BAG3, LAMC3, ATF2, VCP, NDRG1, PUM1, PPT2, HARS, APP, CDK2, TERF2IP, TINF2, ISG15, TERF2, TERF1, ANXA1, SUMO2, SUMO1, AI837181, Pds5a, PPP2R1B, H2AFX, SUPT4H1, EED, EIF4G1, KDR, FDFT1, IFNGR2, ITGB5, COL2A1, COL10A1, ACTG1,
Protein Size: 320

Molecular Weight: 35 kDa

Gene ID: 308

NCBI Accession: NM_001154, NP_001145

UniProt: Q6FHB3

Pathways: Apoptosis