BRAP antibody (Middle Region)

Catalog No. ABIN2774925

This anti-BRAP antibody is a Rabbit Polyclonal antibody detecting BRAP in WB. Suitable for Human, Dog, Rat, Cow, Horse, Mouse, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for BRAP antibody (Middle Region) (ABIN2774925)

Target: BRAP (BRCA1 Associated Protein (BRAP))

Reactivity: Human, Dog, Rat, Cow, Horse, Mouse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRAP Antibody

Binding Specificity: Middle Region

Sequence: YLETQQKINH LPAETRQEIQ EGQINIAMAS ASSPASSGGS GKLPSRKGRS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against BRAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRAP

Target: BRAP (BRCA1 Associated Protein (BRAP))

Alternative Name: BRAP

Background: The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm.
Alias Symbols: BRAP2, IMP, RNF52
Protein Interaction Partner: SYNE2, HMG20A, UBC, NUMA1, TRIM41, TRIM55, TRIM8, CUL1, BRAP, NEDD8, USP15, USP4, KSR1, CUL2, RAF1, MAP2K1, NFKBIB, IKBKB, BRAF, HRAS, CDKN1A, TWIST1, UBE2H, CNKSR1, DDB1, CENPF, BRCA1, CDC14A,
Protein Size: 592

Molecular Weight: 67 kDa

Gene ID: 8315

NCBI Accession: NM_006768, NP_006759

UniProt: Q7Z569