ZNF322A antibody (N-Term)

Catalog No. ABIN2775003

This anti-ZNF322A antibody is a Rabbit Polyclonal antibody detecting ZNF322A in WB. Suitable for Human, Cow, Dog, Horse, Mouse, Rat, Goat, Pig, Rabbit and Guinea Pig.

Quick Overview for ZNF322A antibody (N-Term) (ABIN2775003)

Target: ZNF322A (Zinc Finger Protein 322A (ZNF322A))

Reactivity: Human, Cow, Dog, Horse, Mouse, Rat, Goat, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF322A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF322A Antibody

Binding Specificity: N-Term

Sequence: RTHTGEKPYK CDMCEKTFVQ SSDLTSHQRI HNYEKPYKCS KCEKSFWHHL

Predicted Reactivity: Cow: 91%, Dog: 93%, Goat: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 85%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ZNF322A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF322A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 402 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF322A

Target: ZNF322A (Zinc Finger Protein 322A (ZNF322A))

Alternative Name: ZNF322A

Background: ZNF322 contains four exons and spans 23.2kb in chromosome 6p22.1 region, and transcribes a 2.7kb mRNA that encodes a protein with 402 amino acid residues.Through northern blot analysis, ZNF322 was shown to be expressed in every human tissue examined at adult stage and during embryonic developmental stages from 80 days to 24 weeks. When ZNF322 was overexpressed in COS-7 cells, ZNF322-EGFP fusion protein is detected in the nucleus and cytoplasm. Reporter gene assays show that ZNF322 is a transcriptional activator. Furthermore, overexpression of ZNF322 in COS-7 cells activates the transcriptional activity of SRE and AP-1. Together, these results suggest that ZNF322 is a member of the zinc-finger transcription factor family and may act as a positive regulator in gene transcription mediated by the MAPK signaling pathways.
Alias Symbols: HCG12, ZNF388, ZNF489, ZNF322A
Protein Interaction Partner: APP,
Protein Size: 402

Molecular Weight: 47 kDa

Gene ID: 79692

NCBI Accession: NM_024639, NP_078915

UniProt: Q6U7Q0