AKAP7 antibody (Middle Region)

Catalog No. ABIN2775177

This Rabbit Polyclonal antibody specifically detects AKAP7 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Rabbit and Horse.

Quick Overview for AKAP7 antibody (Middle Region) (ABIN2775177)

Target: AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AKAP7 Antibody

Binding Specificity: Middle Region

Sequence: MKLSKSPWLR KNGVKKIDPD LYEKFISHRF GEEILYRIDL CSMLKKKQSN

Predicted Reactivity: Cow: 83%, Dog: 91%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against AKAP7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKAP7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AKAP7

Target: AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))

Alternative Name: AKAP7

Background: AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
Alias Symbols: AKAP18, AKAP15
Protein Interaction Partner: CEP76, ROPN1, SPA17, PRKAR2B, PRKACB, PRKACA, MEPCE, USP4, PRKAR1A, PRKAR2A,
Protein Size: 326

Molecular Weight: 37 kDa

Gene ID: 9465

NCBI Accession: NM_016377, NP_057461

UniProt: Q9P0M2