DDX3X antibody (N-Term)

Catalog No. ABIN2775180

This Rabbit Polyclonal antibody specifically detects DDX3X in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Pig, Horse and Guinea Pig.

Quick Overview for DDX3X antibody (N-Term) (ABIN2775180)

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Pig, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX3X antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DDX3X Antibody

Binding Specificity: N-Term

Sequence: MSHVAVENAL GLDQQFAGLD LNSSDNQSGG STASKGRYIP PHLRNREATK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DDX3X. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX3X

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 662 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX3X

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Alternative Name: DDX3X

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and m
Alias Symbols: DBX, DDX14, DDX3, HLP2
Protein Interaction Partner: TP53, UBC, SUMO2, SUMO3, STAU1, LGR4, MDM2, RPA3, RPA2, RPA1, EZH2, SUZ12, EED, RNF2, rev, APBB1, NEDD4, EIF3L, SND1, WBP4, EIF3D, RPS23, RPS11, RPS9, RPS7, RPS3, RPS2, PIN1, PARK2, HCVgp1, TARDBP, YWHAQ, UBD, IGSF8, NPM1, LMNA, ICAM1, CD81, SP1, EIF3K, I
Protein Size: 662

Molecular Weight: 73 kDa

Gene ID: 1654

NCBI Accession: NM_001356, NP_001347

UniProt: O00571

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly