DDX1 antibody (N-Term)

Catalog No. ABIN2775201

This Rabbit Polyclonal antibody specifically detects DDX1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Rabbit, Horse, Cow and Pig.

Quick Overview for DDX1 antibody (N-Term) (ABIN2775201)

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DDX1 Antibody

Binding Specificity: N-Term

Sequence: ILGGGDVLMA AETGSGKTGA FSIPVIQIVY ETLKDQQEGK KGKTTIKTGA

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DDX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 740 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX1

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Alternative Name: DDX1

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX1 is a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DBP-RB, UKVH5d
Protein Interaction Partner: HUWE1, FUS, SUMO2, SUMO3, STAU1, UBC, SUMO1, NEDD8, Fbxl16, WWOX, ZBTB1, RPA3, RPA2, RPA1, rev, C14orf166, RTCB, RPL26L1, EIF3K, NELFB, EDC4, IGF2BP3, PDCD6, ABCF1, EIF2B2, EIF2B3, YBX3, RPL27, RFC4, RFC2, QARS, YBX1, NMT1, HNRNPM, MRE11A, KRT18, ILF2, HN
Protein Size: 740

Molecular Weight: 82 kDa

Gene ID: 1653

NCBI Accession: NM_004939, NP_004930

UniProt: Q92499

Pathways: Ribonucleoprotein Complex Subunit Organization