DDX58 antibody (Middle Region)

Catalog No. ABIN2775222

This Rabbit Polyclonal antibody specifically detects DDX58 in WB. It exhibits reactivity toward Human and Horse.

Quick Overview for DDX58 antibody (Middle Region) (ABIN2775222)

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX58 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DDX58 Antibody

Binding Specificity: Middle Region

Sequence: EECHYTVLGD AFKECFVSRP HPKPKQFSSF EKRAKIFCAR QNCSHDWGIH

Predicted Reactivity: Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against DDX58. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DDX58

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 925 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DDX58

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Alternative Name: DDX58

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein
Alias Symbols: DKFZp434J1111, DKFZp686N19181, FLJ13599, RIG-I
Protein Interaction Partner: MAVS, TRIM25, RNF135, TRIM26, UBC, MEX3C, USP21, USP3, TBK1, IKBKE, IKBKG, Casp12, NLRC5, DDX58, USP4, MBP, IRF3, SRC, TSPAN6, TRIM32, ISG15, PRKCG, PRKCB, PRKCA, WRNIP1, RNF31, RAI14, RBCK1, PRKRIR, UBE2D3, UBE2D2, UBE2D1, UBE2K, CYLD,
Protein Size: 925

Molecular Weight: 106 kDa

Gene ID: 23586

NCBI Accession: NM_014314, NP_055129

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C