WRNIP1 antibody (N-Term)

Catalog No. ABIN2775244

The Rabbit Polyclonal anti-WRNIP1 antibody has been validated for WB. It is suitable to detect WRNIP1 in samples from Human, Mouse, Rat, Dog, Cow, Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for WRNIP1 antibody (N-Term) (ABIN2775244)

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WRNIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WRNIP1 Antibody

Binding Specificity: N-Term

Sequence: PGAKRRRLSE SSALKQPATP TAAESSEGEG EEGDDGGETE SRESYDAPPT

Predicted Reactivity: Cow: 79%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 79%, Rat: 100%, Yeast: 77%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against WRNIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 640 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WRNIP1 antibody (ABIN2775244)

Tsurimoto, Shinozaki, Yano, Seki, Enomoto: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).

Target Details for WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Alternative Name: WRNIP1

Background: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.
Alias Symbols: FLJ22526, RP11-420G6.2, WHIP, bA420G6.2
Protein Interaction Partner: UBC, RNF31, PIN1, ELP2, ELP3, TRIM28, HDAC11, EPAS1, VCP, SRSF4, SMAD2, RAD18, NUP107, WRNIP1, FGFR1OP, POLD1, ABL1, SUMO2, TOLLIP, DDX58, USP11, OSBPL10, USP25, POLD4, POLD2, WRN,
Protein Size: 640

Molecular Weight: 72 kDa

Gene ID: 56897

NCBI Accession: NM_130395, NP_569079

UniProt: Q96S55