C10orf2 antibody (Middle Region)
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- Target See all C10orf2 (C10ORF2) Antibodies
- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This C10orf2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GDVGVFPLEF NKNSLTFSIP PKNKARLKKI KDDTGPVAKK PSSGKKGATT
- Predicted Reactivity
- Cow: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against PEO1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PEO1
- Top Product
- Discover our top product C10ORF2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 684 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
- Alternative Name
- PEO1 (C10ORF2 Products)
- Synonyms
- ATXN8 antibody, IOSCA antibody, MTDPS7 antibody, PEO antibody, PEO1 antibody, PEOA3 antibody, SANDO antibody, SCA8 antibody, TWINL antibody, C6H10orf2 antibody, D19Ertd626e antibody, Twinl antibody, twinkle mtDNA helicase L homeolog antibody, twinkle mtDNA helicase antibody, twnk.L antibody, TWNK antibody, Twnk antibody
- Background
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Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars.Twinkle is a mitochondrial protein with structural similarity to the phage T7 primase/helicase (GP4) and other hexameric ring helicases. The twinkle protein colocalizes with mtDNA in mitochondrial nucleoids, and its name derives from the unusual localization pattern reminiscent of twinkling stars (Spelbrink et al., 2001 [PubMed 11431692]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-213 BG473173.1 6-218 214-1706 BX640829.1 215-1707 1707-3630 BC033762.1 719-2642
Alias Symbols: C10orf2, FLJ21832, PEO, PEOA3, SANDO, TWINL, PEO1, SCA8, ATXN8, IOSCA, MTDPS7
Protein Interaction Partner: ZBTB1, BMI1, SMAD9, ICT1, SQSTM1, AKTIP,
Protein Size: 684 - Molecular Weight
- 77 kDa
- Gene ID
- 56652
- NCBI Accession
- NM_021830, NP_068602
- UniProt
- Q96RR1
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