DMPK antibody (Middle Region)

Catalog No. ABIN2775281

This anti-DMPK antibody is a Rabbit Polyclonal antibody detecting DMPK in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig and Horse. This Primary Antibody has been cited in 1 publication.

Quick Overview for DMPK antibody (Middle Region) (ABIN2775281)

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMPK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DMPK Antibody

Binding Specificity: Middle Region

Sequence: TRLGRGGAGD FRTHPFFFGL DWDGLRDSVP PFTPDFEGAT DTCNFDLVED

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DMPK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DMPK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 629 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DMPK antibody (ABIN2775281)

Ramasamy, Ren, Mench, Regan: "Impact of initial biofilm growth on the anode impedance of microbial fuel cells." in: Biotechnology and bioengineering, Vol. 101, Issue 1, pp. 101-8, (2008) (PubMed).

Target Details for DMPK

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Alternative Name: DMPK

Background: The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium chann
Alias Symbols: DM, DM1, DM1PK, DMK, MDPK, MT-PK
Protein Interaction Partner: HOXA2, LGR4, GEMIN4, UBC, HSP90AA1, ATXN1, ATN1, UBQLN4, PIN1, ANXA7, TK1, SMN1, RPS10, GABARAP, FXYD1, HSPB2, PPP1R12A, CELF1, PLN, RAF1, RAC1, RARG, SP1,
Protein Size: 629

Molecular Weight: 69 kDa

Gene ID: 1760

NCBI Accession: NM_004409, NP_004400

UniProt: Q09013

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development