HBZ antibody (N-Term)

Catalog No. ABIN2775308

This anti-HBZ antibody is a Rabbit Polyclonal antibody detecting HBZ in WB and IHC. Suitable for Human, Rat, Mouse, Horse, Cow, Goat, Pig and Rabbit.

Quick Overview for HBZ antibody (N-Term) (ABIN2775308)

Target: HBZ (Hemoglobin, zeta (HBZ))

Reactivity: Human, Rat, Mouse, Horse, Cow, Goat, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HBZ Antibody

Binding Specificity: N-Term

Sequence: ERLFLSHPQT KTYFPHFDLH PGSAQLRAHG SKVVAAVGDA VKSIDDIGGA

Predicted Reactivity: Cow: 93%, Goat: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HBZ. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HBZ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 142 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HBZ

Target: HBZ (Hemoglobin, zeta (HBZ))

Alternative Name: HBZ

Background: Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult like. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.Zeta-globin (HBZ ) is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult like. The zeta-globin gene is a member of the human alpha-globin gene cluster that involves 4 functional genes and 3 nonfunctional pseudogenes. The order of genes is: 5'-zeta -- pseudozeta -- pseudoalpha2 -- pseudoalpha1 -- alpha2 -- alph1 -- theta1-3'.
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-9, KRTAP10-7, KHDRBS2, KRT40, DOCK8, HBD, UPF2, HNRNPD, VCAM1, ITGA4, FN1, APP, SP1, JUND, IKBKG, HBZ, HBB, FGFR3,
Protein Size: 142

Molecular Weight: 16 kDa

Gene ID: 3050

NCBI Accession: NM_005332, NP_005323

UniProt: P02008