MAGEA8 antibody (N-Term)

Catalog No. ABIN2775309

This Rabbit Polyclonal antibody specifically detects MAGEA8 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for MAGEA8 antibody (N-Term) (ABIN2775309)

Target: MAGEA8 (Melanoma Antigen Family A, 8 (MAGEA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAGEA8 Antibody

Binding Specificity: N-Term

Sequence: EEVTDSGSPS PPQSPEGASS SLTVTDSTLW SQSDEGSSSN EEEGPSTSPD

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGEA8. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEA8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA8

Target: MAGEA8 (Melanoma Antigen Family A, 8 (MAGEA8))

Alternative Name: MAGEA8

Background: MAGEA8 is a member of the MAGEA family. The members of this family with 50 to 80 % sequence identity to each other. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Alias Symbols: MAGE8, MGC2182, CT1.8
Protein Interaction Partner: MTUS2, PKD2, MAGEB4, LMO2, BEX5, LXN, GCA, UBE3A, UBC,
Protein Size: 318

Molecular Weight: 35 kDa

Gene ID: 4107

NCBI Accession: NM_005364, NP_005355

UniProt: Q9BUN9