MAGEA8 antibody (AA 1-80)

Catalog No. ABIN7229518

The Rabbit Polyclonal anti-MAGEA8 antibody is suitable to detect MAGEA8 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for MAGEA8 antibody (AA 1-80) (ABIN7229518)

Target: MAGEA8 (Melanoma Antigen Family A, 8 (MAGEA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MAGEA8 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-MAGA8 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGA8 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGA8 protein at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAGEA8

Target: MAGEA8 (Melanoma Antigen Family A, 8 (MAGEA8))

Alternative Name: MAGA8

Background: Melanoma-associated antigen 8, Cancer/testis antigen 1.8, CT1.8, MAGE-8 antigenMAGEA8 (MAGE Family Member A8) is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of MAGEA8 family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 34kD

Gene ID: 4107

UniProt: P43361