Follistatin antibody (Middle Region)

Catalog No. ABIN2775336

This anti-Follistatin antibody is a Rabbit Polyclonal antibody detecting Follistatin in WB. Suitable for Human, Mouse, Rat, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Cow, Zebrafish (Danio rerio) and Pig.

Quick Overview for Follistatin antibody (Middle Region) (ABIN2775336)

Target: Follistatin (FST)

Reactivity: Human, Mouse, Rat, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Cow, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Follistatin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Follistatin Antibody

Binding Specificity: Middle Region

Sequence: ALLKARCKEQ PELEVQYQGR CKKTCRDVFC PGSSTCVVDQ TNNAYCVTCN

Predicted Reactivity: Cow: 92%, Dog: 100%, Goat: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against FST. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FST

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 317 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Follistatin

Target: Follistatin (FST)

Alternative Name: FST

Background: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
Alias Symbols: FS
Protein Interaction Partner: INHBA, BMPR2, BMPR1A, C8orf33, TK1, MEST, INHBE, INHA, FN1, BMP5, TXN,
Protein Size: 317

Molecular Weight: 35 kDa

Gene ID: 10468

NCBI Accession: NM_006350, NP_006341

UniProt: B5BU94

Pathways: Negative Regulation of Hormone Secretion