SARDH antibody (Middle Region)

Catalog No. ABIN310324

This Rabbit Polyclonal antibody specifically detects SARDH in WB and IHC. It exhibits reactivity toward Mouse, Human, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig and Horseand has been mentioned in 1 publication.

Quick Overview for SARDH antibody (Middle Region) (ABIN310324)

Target: SARDH (Sarcosine Dehydrogenase (SARDH))

Reactivity: Mouse, Human, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARDH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SARDH Antibody

Binding Specificity: Middle Region

Sequence: DHPRWIRERS HESYAKNYSV VFPHDEPLAG RNMRRDPLHE ELLGQGCVFQ

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SARDH. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SARDH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 611 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SARDH antibody (ABIN310324)

Khan, Rajendiran, Ateeq, Asangani, Athanikar, Yocum, Mehra, Siddiqui, Palapattu, Wei, Michailidis, Sreekumar, Chinnaiyan: "The role of sarcosine metabolism in prostate cancer progression." in: Neoplasia (New York, N.Y.), Vol. 15, Issue 5, pp. 491-501, (2013) (PubMed).

Target Details for SARDH

Target: SARDH (Sarcosine Dehydrogenase (SARDH))

Alternative Name: SARDH

Background: The function remains known.
Alias Symbols: DMGDHL1, FLJ36475, SAR, SARD, SDH, BPR-2
Protein Interaction Partner: UBE2N, FKBP4,
Protein Size: 918

Molecular Weight: 101 kDa

Gene ID: 1757

NCBI Accession: NM_001134707

UniProt: Q9UL12