GREM1 antibody (C-Term)

Catalog No. ABIN2775383

This anti-GREM1 antibody is a Rabbit Polyclonal antibody detecting GREM1 in WB. Suitable for Human, Mouse, Rat, Rabbit, Cow, Dog, Goat, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for GREM1 antibody (C-Term) (ABIN2775383)

Target: GREM1 (Gremlin 1 (GREM1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Goat, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GREM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GREM1 Antibody

Binding Specificity: C-Term

Sequence: EEGSFQSCSF CKPKKFTTMM VTLNCPELQP PTKKKRVTRV KQCRCISIDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Grem1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Grem1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 184 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GREM1

Target: GREM1 (Gremlin 1 (GREM1))

Alternative Name: Grem1

Background: Grem1 is a cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. It down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis.
Alias Symbols: Cktsf1b1, Drm, ld
Protein Size: 184

Molecular Weight: 21 kDa

Gene ID: 23892

NCBI Accession: NM_011824, NP_035954

UniProt: O70326

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location